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Karyopharm Therapeutics Inc

KPTI | US

8.77

USD

-0.05

-0.57%

KPTI | US

About Karyopharm Therapeutics Inc

Sector

Healthcare

Industry

Drug Manufacturers-Specialty & Generic

Earnings date

30/06/2024

As of date

06/03/2026

Close

8.77

Open

8.72

High

9.11

Low

8.57

Karyopharm Therapeutics Inc. a commercial-stage pharmaceutical company discovers develops and commercializes drugs directed against nuclear export for the treatment of cancer and other diseases. The company discovers develops and commercializes novel and Selective Inhibitor of Nuclear Export (SINE) compounds that inhibit the nuclear export protein exportin 1 (XPO1). Its lead compound include XPOVIO in combination with bortezomib and dexamethasone for the treatment of adult patients with multiple myeloma; in combination with dexamethasone for the treatment of adult patients with relapsed or refractory multiple myeloma; and for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL). The company is also developing Selinexor for treating hematological and solid tumor malignancies including multiple myeloma endometrial cancer myelofibrosis and DLBCL; and ELTANEXOR for treating Myelodysplastic Neoplasms as well as verdinexor KPT-9274 and IL-12 compounds. The company has license agreement with Menarini Group to develop and commercialize selinexor for human oncology indications; license agreement with Antengene Therapeutics Limited to develop and commercialize selinexor eltanexor and KPT-9274 for the treatment and/or prevention of human oncology indications as well as verdinexor for the diagnosis treatment and/or prevention of human non-oncology indications; and distribution agreement for the commercialization of XPOVIO with FORUS Therapeutics Inc. The company was incorporated in 2008 and is headquartered in Newton Massachusetts.

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KPTI | US

Risk
100.2
Sharpe
0.39
Luna's Score
48/100
Recommendation
Hold

Luna says (KPTI | US)

What's Working

Low Market Beta (-0.4 to 0.8)

Low Debt to Equity (< 0.25)

Strong Revenue Growth (> 10%)

What's not Working

Price Below SMA10D

High 6-Month Volatility (>65%)

Smallcap (300M - 2B USD)

High Short percentage (> 15%)

Rich in Valuation (Price to Book > 8)

Weak Operating Margin (< 10%)

Volatility Signals

Bullish: Stable Volatility (6-month <= 1-month volatility) is positive for the stock performance.

Risk Meter

10 days

50.3%

1 month

100.2%

3 months

84.4%

6 months

84.7%

Returns

Fundamental Ratios

PE

-

Fwd. PE

-

Price to book

12.05

Debt to equity

-1.48

Debt to assets

0.91

Ent. to EBITDA

-1.85

Ent. to rev.

1.04

PEG

-0.15

Other Fundamentals

EBITDA

-130.61M

MarketCap

1.09B

MarketCap(USD)

1.09B

Div. yield

-

Op. margin

-65.72

Erngs. growth

-

Rev. growth

13.90

Ret. on equity

-891.05

Short ratio

28.47

Short perc.

15.21

Market Sentiment (SMA and Price signals)

Short-term: Bullish (SMA10D > SMA1M)

Intermediate-term: Bullish (SMA1M > SMA3M)

Long-term: Bullish (SMA6M > SMA12M)

SMAs: Stock Price Trends

Range10D

2.42

Range1M

5.09

Range3M

5.29

Volumes: Market Activity

Rel. volume

0.94

Price X volume

6.36M

Peers

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Industry
Close
Marketcap
Day Return
PE Ratio
Debt to Equity
 
 
 
 
 
 
 
 
Collegium Pharmaceutical IncCOLLDrug Manufacturers-Specialty & Generic37.291.20B0.03%14.45258.31%
Assertio Therapeutics IncASRTDrug Manufacturers-Specialty & Generic11.721.12B-1.92%n/a30.76%
Pacira Pharmaceuticals IncPCRXDrug Manufacturers-Specialty & Generic221.01B-3.76%13.0573.76%
Amphastar Pharmaceuticals IncAMPHDrug Manufacturers-Specialty & Generic19.34946.93M-5.38%16.1487.00%
OPKO Health IncOPKDrug Manufacturers-Specialty & Generic1.18816.54M0.85%n/a19.31%
PAR Technology CorporationPARDrug Manufacturers-Specialty & Generic19.22697.38M-1.54%n/a65.19%
Aceto CorporationACETDrug Manufacturers-Specialty & Generic7.29600.70M-2.28%n/a8.14%
Ironwood Pharmaceuticals IncIRWDDrug Manufacturers-Specialty & Generic3.5559.09M-3.31%55.00-199.01%
Elite Pharmaceuticals IncELTPDrug Manufacturers-Specialty & Generic0.392422.34M-2.00%29.500.00%
Aquestive Therapeutics IncAQSTDrug Manufacturers-Specialty & Generic4.22384.27M-0.94%n/a-329.45%
  • 1

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  • 1

Industry Comparison

ParameterCompanyIndustryIndicator
Enterprise to EBITDA-1.8524.85Cheaper
Ent. to Revenue1.04361.91Cheaper
PE Ratio-30.05-
Price to Book12.0513.15Par
Dividend Yield-2.94-
Std. Deviation (3M)84.3865.24Riskier
Debt to Equity-1.48-1.88Expensive
Debt to Assets0.910.48Expensive
Market Cap1.09B3.71BEmerging
  • 1

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